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Aggregate aggrephagy regulator patterns guide intercellular communication of tumor microenvironment that contribute to gastric cancer progression and immunotherapy

2023-09-18

Abstract excerpt

<h4>Background: </h4> Aggregate autophagy plays a key role in cancer progression; however, how aggregate autophagy plays a role in tumor microenvironment (TME) remains to be elucidated. Methods 30571 single cells from the single-cell RNA-seq data of 13 gastric cancer (GC) specimens were analyzed by nonnegative matrix factorization (NMF) to find out the effects of 44 aggregate autophagy-related genes on major TME...

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Literature Corpus work
fcc66a0d-2e12-5522-a309-950528fa0b5e
DOI
10.21203/rs.3.rs-3345477/v1
Open publication

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