Article

Proteomic profiling of serum exosomes reveals acute phase response and promotion of inflammatory and platelet activation pathways in patients with heat stroke

2022-05-31

Abstract excerpt

<title>Abstract</title> <p><italic>Background</italic>: The pathological mechanism of heat stroke (HS) involves the acute phase response, unbalanced immunological/inflammatory reactions, and coagulation initiation, especially platelet activation. Although exosomes contain proteins involved in these biological processes, their protein cargo levels and potential roles in HS remain unknown. This study explored the s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fc8bcbc3-e72e-5097-9607-9bef4377c817
DOI: 10.21203/rs.3.rs-1694452/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Proteomic profiling of serum exosomes reveals acute phase response and promotion of inflammatory and platelet activation pathways in patients with heat strokeDOI 10.21203/rs.3.rs-1694452/v1Read

Exosomes Derived From Heat Stroke Cases Carry miRNAs Associated With Inflammation and Coagulation CascadeSemantic proximity Read

Isolation and identification of serum exosomes and correlation of its contents with acute ischemic strokeSemantic proximity Read

Identification of key genes and immune characteristics of SASP in acute ischemic strokeSemantic proximity Read

Single-cell sequencing-based study of ferroptosis mechanisms in heat stroke: identification of key biomarkers and dynamic analysis of the immune microenvironmentSemantic proximity Read

Identification of exosome-related differentially expressed genes in ischemic strokeSemantic proximity Read

Serum Olink Proteomics-Based Identification of Protein Biomarkers Associated with the Immune Response in Ischemic StrokeSemantic proximity Read

Differential Expression Pattern of Exosome Long Non-Coding RNAs (lncRNAs) and MicroRNAs (miRNAs) in Vascular Endothelial Cells Under Heat StrokeSemantic proximity Read

Identification of Potential Therapeutic targets for Stroke and Its Subtypes by Integrating Proteomes and Genetics from Human PlasmaSemantic proximity Read

Association of Serum Biomarkers with Post-Thrombolytic Early Neurological Improvement in Stroke: A Comprehensive Protein Microarray Analysis From INTRECIS StudySemantic proximity Read

Novel Therapeutic Strategy Targeting Hspa8 for Ischemic Brain InjurySemantic proximity Read

Identification of endoplasmic reticulum stress genes in human stroke based on bioinformatics and machine learningSemantic proximity Read

New insight in understanding and exploring optimal biomarkers in stroke: Key diagnostic markers for clinical treatmentSemantic proximity Read