Article

Exploration of Kras Mutations and Their Potential for Being a Target Molecule in Cancer Chemotherapy

2023-01-01

Abstract excerpt

The Rat sarcoma virus (RAS) family of proteins, which includes the Kristen Rat sarcoma virus (KRAS), is linked to nearly one-fourth of all human cancers. KRAS mutations, in particular, are associated with Non-Small Cell Lung Carcinoma (NSCLC), colorectal cancer, adenocarcinomas, ovarian carcinoma, and endometrial tumors. KRAS activates 80 different signaling pathways, including Mitogen-activated protein kinases (M...

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Literature Corpus work: fc83a5da-c37b-56fa-8f52-950f2e5e187d
DOI: 10.4236/jct.2023.146022

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