Back to search

Article

Flipping the switch on some of the slowest mutating genomes: Direct measurements of plant mitochondrial and plastid mutation rates in <i>msh1</i> mutants

2025-01-12

Abstract excerpt

Plant mitochondrial and plastid genomes have exceptionally slow rates of sequence evolution, and recent work has identified an unusual member of the MutS gene family (“plant MSH1 ”) as being instrumental in preventing point mutations in these genomes. However, the eXects of disrupting MSH1 -mediated DNA repair on “germline” mutation rates have not been quantified. Here, we used Arabidopsis thaliana mutation ac...

Identifiers and source

Literature Corpus work
fc27dfc9-2f62-5a74-ae09-ff422d321899
DOI
10.1101/2025.01.08.631957
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Flipping the switch on some of the slowest mutating genomes: Direct measurements of plant mitochondrial and plastid mutation rates in <i>msh1</i> mutantsDOI 10.1101/2025.01.08.631957
Sorting of mitochondrial and plastid heteroplasmy in Arabidopsis is extremely rapid and depends on MSH1 activitySemantic proximity
MSH1 is required for maintenance of the low mutation rates in plant mitochondrial and plastid genomes.Semantic proximity
Investigating low frequency somatic mutations in <i>Arabidopsis</i> with Duplex SequencingSemantic proximity
Double-strand break repair processes drive evolution of the mitochondrial genome in Arabidopsis.Semantic proximity
DNA mismatch repair preferentially protects genes from mutation.Semantic proximity
Nanorate sequencing reveals the <i>Arabidopsis</i> somatic mutation landscapeSemantic proximity
Disruption of recombination machinery alters the mutational landscape in plant organellar genomes.Semantic proximity
Nanorate sequencing reveals the Arabidopsis somatic mutation landscape.Semantic proximity
Causes of Mutation Rate Variability in Plant Genomes.Semantic proximity
Mutational consequences of perturbing DNA repair and chromatin state in <i>Arabidopsis</i>Semantic proximity
Exploring the Relationship Between Gene Expression and Low-Frequency Somatic Mutations in Arabidopsis with Duplex Sequencing.Semantic proximity
Quantitative and sensitive sequencing of somatic mutations induced by a maize transposonSemantic proximity
Select a neighboring publication to make it the new centre.