Article

The Cystic Fibrosis treatment, Trikafta, affects growth, viability, and cell wall of <i>Aspergillus fumigatus</i> biofilms

2023-06-21

Abstract excerpt

<h4>ABSTRACT</h4> People with Cystic Fibrosis (pwCF) commonly test positive for the pathogenic fungus, Aspergillus fumigatus, which is associated with a decline in lung function. Trikafta is a recently approved therapy for pwCF that improves quantity and function of the CFTR protein, however, it is not known how Trikafta affects microbial communities in the lung. Therefore, the aim of this study was to determine...

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Literature Corpus work: fbda5923-064e-5560-8488-964917ab3fb6
DOI: 10.1101/2023.06.20.545692

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