Article

Phosphate Limitation Modulates <i>Vibrio cholerae</i> Outer Membrane Vesicle Formation, Composition and Toxicity

2025-11-13

Abstract excerpt

Vibrio cholerae inhabits phosphorus-poor aquatic environments and host intestine, where it expresses genes regulated by the PhoB/PhoR two-component system in response to inorganic phosphate (Pi) limitation. Like other Gram-negative bacteria, V. cholerae releases outer membrane vesicles (OMVs), which carry proteins, lipids, and nucleic acids that contribute to adaptation, survival, and pathogenesis. Here, we inves...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4b768031-3390-5443-b3f5-f7690e87ee2f
DOI: 10.1101/2025.11.13.688205

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Phosphate Limitation Modulates <i>Vibrio cholerae</i> Outer Membrane Vesicle Formation, Composition and ToxicityDOI 10.1101/2025.11.13.688205Read

A comparative proteomic analysis of Vibrio cholerae O1 wild-type cells versus a phoB mutant showed that the PhoB/PhoR system is required for full growth and rpoS expression under inorganic phosphate abundance.Semantic proximity Read

Versatility of <i>Campylobacter jejuni</i> Bf extracellular vesicles in regulating adaptation and virulence under combined thermal and oxidative stressSemantic proximity Read

A ToxR-dependent role for the putative phosphoporin VCA1008 in bile salt resistance in Vibrio cholerae El Tor N16961.Semantic proximity Read

Interplay between genetic regulation of phosphate homeostasis and bacterial virulence.Semantic proximity Read

Metabolomics and lipidomics analyses delineating Hfq deletion- induced metabolic alterations in Vibrio alginolyticusSemantic proximity Read

<i>In situ</i> NMR reveals a pH sensor motif in an outer membrane protein that drives bacterial vesicle productionSemantic proximity Read

Accumulation of ornithine lipids in Vibrio cholerae under phosphate deprivation is dependent on VC0489 (OlsF) and PhoBR system.Semantic proximity Read

Proteomic Analysis Reveals the Phenotypic Heterogeneity and Tolerance Mechanisms of Halophilic Vibrio parahaemolyticus Under Dual Stress of Low Salinity and Bile Salts in the Human Intestine.Semantic proximity Read

Mapping bacterial extracellular vesicle research: insights, best practices and knowledge gapsSemantic proximity Read

Single cell RNA-seq reveals that the Vibrio cholerae MakA toxin is required for killing of Tetrahymena pyriformis and for survival in protozoan expelled food vacuolesSemantic proximity Read

PhoB Activates Escherichia coli O157:H7 Virulence Factors in Response to Inorganic Phosphate LimitationSemantic proximity Read

Identification of genes required for long term survival of <i>L. pneumophila</i> in waterSemantic proximity Read