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CD90 Is Regulated by NOTCH1 and Hallmarks a More Aggressive Intrahepatic Cholangiocarcinoma Phenotype

2022-01-19

Abstract excerpt

<h4>Background: </h4> Intrahepatic Cholangiocarcinoma (iCCA) is characterized by a strong stromal reaction playing a role in tumor progression. Thymus cell antigen 1 ( THY1 ), also called Cluster of Differentiation 90 (CD90), is a key regulator of cell-cell and cell-matrix interaction. In iCCA, CD90 has been reported to be associated with a poor prognosis. In an iCCA PDX model, we recently found that CD90 was down...

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Literature Corpus work
fb61b58b-6b7c-5140-97b0-6661a899a74c
DOI
10.21203/rs.3.rs-1261041/v1
Open publication

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CD90 Is Regulated by NOTCH1 and Hallmarks a More Aggressive Intrahepatic Cholangiocarcinoma PhenotypeDOI 10.21203/rs.3.rs-1261041/v1
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