Article

Autologous cell therapy with CD133+ bone marrow-derived stem cells for Asherman Syndrome: a phase 1/2 trial

2025-04-09

Abstract excerpt

<title>Abstract</title> <p> Autologous CD133 + bone marrow-derived stem cell (BMDSC) therapy has been designated an Orphan Drug by the EMA and FDA for the treatment of Asherman Syndrome (AS). This phase 1/2, non-randomized, open-label, single-arm trial assessed the safety, efficacy and biological plausibility of this novel therapy in 20 infertile women with moderate to severe AS unresponsive to prior hysteroscop...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fb1bb358-c028-5c85-b75b-4dd3608646eb
DOI: 10.21203/rs.3.rs-5886137/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Autologous cell therapy with CD133+ bone marrow-derived stem cells for Asherman Syndrome: a phase 1/2 trialDOI 10.21203/rs.3.rs-5886137/v1Read

Clinical Efficacy and Safety of Stem Cell-Based Therapy in Treating Asherman Syndrome: A System Review and Meta-AnalysisSemantic proximity Read

Endometrial Regeneration in Asherman's Syndrome: Clinical and Translational evidence of Stem Cell TherapiesSemantic proximity Read

Decoding the endometrial niche of Asherman’s Syndrome at single-cell resolutionSemantic proximity Read

Effects of uterus derived mesenchymal stem cells and their exosomes on asherman’s syndromeSemantic proximity Read

Decoding the endometrial niche of Asherman’s Syndrome at single-cell resolutionSemantic proximity Read

Strategies for managing Asherman's syndrome and endometrial atrophy: Since the classical experimental models to the new bioengineering approachSemantic proximity Read

Asherman syndrome--one century later.Semantic proximity Read

Autologous Human Mesenchymal Stem Cell-Based Therapy in Infertility: New Strategies and Future PerspectivesSemantic proximity Read

Perivascular Stem Cell-Derived Cyclophilin A Improves Uterine Environment with Asherman's Syndrome via HIF1α-Dependent Angiogenesis.Semantic proximity Read

The Concept behind the Suitability of Menstrual Blood-Derived Stem Cells for the Management of Vaginal Atrophy among BRCA Mutation Carriers after RRSO.Semantic proximity Read

Asherman's Syndrome: it may not be all our fault.Semantic proximity Read

Recent Advances in Understandings Towards Pathogenesis and Treatment for Intrauterine Adhesion and Disruptive Insights from Single-Cell AnalysisSemantic proximity Read