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Decoding the microbiome and resistome of advanced chronic liver disease through long-read metagenomics

2025-12-09

Abstract excerpt

<h4>Introduction</h4> Patients with advanced chronic liver disease (ACLD) and underlying cirrhosis frequently require repeated courses of antimicrobial therapy, with both the frequency and spectrum of antimicrobial exposure increasing alongside disease progression. In this population, impaired immune function and increased intestinal barrier dysfunction contribute to a heightened susceptibility of multidrug-resis...

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Literature Corpus work
faa0b221-8006-513c-b6bb-55fc034c85a2
DOI
10.64898/2025.12.09.693164
Open publication

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