Article

Revisiting Bupropion Anti-inflammatory Action: Involvement of the TLR2/TLR4 and JAK2/STAT3 

2021-03-22

Abstract excerpt

<title>Abstract</title> <p>There are accumulating reports regarding poor response to the common antidepressant therapy. Antidepressant resistance has often been associated with activation of the inflammatory system. Accordingly, major depressive disorder (MDD) patients displaying inflammation prior to the treatment are less responsive to antidepressants. We hypothesized that the inefficacy of antidepressant thera...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fa8fc0e7-0c41-550f-a7ec-b312a1cb8b31
DOI: 10.21203/rs.3.rs-313044/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Revisiting Bupropion Anti-inflammatory Action: Involvement of the TLR2/TLR4 and JAK2/STAT3 DOI 10.21203/rs.3.rs-313044/v1Read

Revisiting bupropion anti-inflammatory action: involvement of the TLR2/TLR4 and JAK2/STAT3Semantic proximity Read

Anti-Depression a Systematic Review of Analytical methods in PharmaceuticalsSemantic proximity Read

AI Perspectives on the Present and Future of Antidepressant Pharmaceutical Treatment Based on Anti-inflammatory Strategies: A Scoping Review of Randomised Controlled Clinical TrialsSemantic proximity Read

Brexanolone therapeutics in post-partum depression involves inhibition of systemic inflammatory pathwaysSemantic proximity Read

Antidepressant therapies inhibit inflammation and microglial M1-polarization.Semantic proximity Read

Proinflammatory Cytokines: A Common Denominator in Depression and Somatic Symptoms?Semantic proximity Read

From Immune Activation to Cell Death: Investigating the Pro-inflammatory Phenotype of PBMCs in Major Depressive DisorderSemantic proximity Read

Fluoxetine as an Anti-Inflammatory Therapy in SARS-CoV-2 InfectionSemantic proximity Read

Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTORSemantic proximity Read

Betaine Inhibits NLRP3 Inflammasome Hyperactivation and Regulates Microglial M1/M2 Phenotypic Differentiation, Thereby Attenuating Lipopolysaccharide-Induced Depression-Like Behavior.Semantic proximity Read

Interleukin-12 Dynamic Changes as a Predictive Biomarker of Antidepressant Response in Adolescents with MDD and Comorbid NSSI: A Prospective Longitudinal StudySemantic proximity Read

T helper-1 activation via interleukin-16 is a key phenomenon in the acute phase of severe, first-episode major depressive disorder and suicidal behaviorsSemantic proximity Read