Article
Aspergillus fumigatus pan-genome analysis identifies genetic variants associated with human infection.
Nature microbiology - 1 Dec 2021
Barber Amelia E, Sae-Ong Tongta, Kang Kang, Seelbinder Bastian, Li Jun, Walther Grit, Panagiotou Gianni, Kurzai Oliver
Abstract excerpt
Aspergillus fumigatus is an environmental saprobe and opportunistic human fungal pathogen. Despite an estimated annual occurrence of more than 300,000 cases of invasive disease worldwide, a comprehensive survey of the genomic diversity present in A. fumigatus-including the relationship between clinical and environmental isolates and how this genetic diversity contributes to virulence and antifungal drug...
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