Article

Adiposity, Not Galectin-3, Is the Independent Causal Driver of Periodontitis: A Multivariable Mendelian Randomization Study

2026-03-26

Abstract excerpt

<title>Abstract</title> <p>Objectives: Using Mendelian randomization (MR) to evaluate the causal relationships among circulating galectin-3 (Gal-3), obesity, and periodontitis, and to determine whether Gal-3 is an independent risk factor or a downstream metabolic biomarker. Materials and methods: Univariable Mendelian randomization (UVMR) was performed using genetic instruments for circulating Gal-3 (n = 21,758...

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Literature Corpus work: fa08ca38-bb22-5aa1-9eb1-ec364adc4d90
DOI: 10.21203/rs.3.rs-9116792/v1

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