Article

Mutation in CDC42 gene set as a response biomarker for immune checkpoint inhibitor therapy

2023-11-11

Abstract excerpt

<h4>Background</h4> Immunotherapy has proven notably effective in treating tumors across diverse patient populations. However, some patients do not respond to immune checkpoint inhibitors (ICIs). Thus, there is a need for reliable biomarkers that can predict clinical responses to ICI treatment accurately. <h4>Methods</h4> Our focus is on CDC42, a protein that stimulates multiple signaling pathways, promoting tumor...

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Literature Corpus work: f989b2ad-f53b-54e9-8788-3511ca31c260
DOI: 10.1101/2023.11.10.23298355

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