Article

IFN-γ mediated signaling improves fungal clearance in experimental pulmonary mucormycosis.

2021-04-06

Abstract excerpt

<title>Abstract</title> <p>We established three immunocompetent murine models of pulmonary mucormycosis to determine the involvement of the adaptive immune response in host resistance in pulmonary mucormycosis, a rapidly fatal disease caused mainly by <italic>Rhizopus</italic> spp. Immunocompetent BALB/c, C57BL/6, and Swiss mice were inoculated with <italic>R. oryzae</italic> via the intratracheal route. The inoc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f8f7a26b-a929-577e-9f23-48efb0d911fe
DOI: 10.21203/rs.3.rs-366255/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

IFN-γ mediated signaling improves fungal clearance in experimental pulmonary mucormycosis.DOI 10.21203/rs.3.rs-366255/v1Read

[Immunopathogenesis of invasive mould infections].Semantic proximity Read

Early adjunct anti-PD-L1 immunotherapy improves outcomes and restores infection-induced immune paralysis in mice with invasive pulmonary mucormycosisSemantic proximity Read

Anti-Immune Strategies of Pathogenic FungiSemantic proximity Read

The Immune Interplay between the Host and the Pathogen inAspergillus fumigatusLung InfectionSemantic proximity Read

CD137 Signaling is Critical in Fungal Clearance During Systemic <em>Candida albicans</em> InfectionSemantic proximity Read

MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatusSemantic proximity Read

Analysis of chronic host-aspergilloma interactions using a novel mouse modelSemantic proximity Read

Cryptococcus inositol utilization modulates the host protective immune response during brain infection.Semantic proximity Read

Cellular and humoral peritoneal immunity to Mesocestoides vogae metacestodes infection in mice.Semantic proximity Read

The Effects of Paracoccidioides brasiliensis Infection on GM-CSF- and M-CSF-Induced Mouse Bone Marrow-Derived Macrophage from Resistant and Susceptible Mice Strains.Semantic proximity Read

IL-18 production is required for the generation of a Th1 response during chromoblastomycosisSemantic proximity Read

Dissemination of influenza B virus to the lower respiratory tract of mice is restricted by the interferon responseSemantic proximity Read