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Towards H&E Referenced Multiplex Immunofluorescence Interpretation: Spatial Co-localization, Cell Feature Validation, and Virtual H&E Generation

2025-01-06

Abstract excerpt

<title>Abstract</title> <p>Multiplexed Immunofluorescence (MxIF) enables detailed immune cell phenotyping, providing critical insights into cell behavior within the tumor immune microenvironment (TIME). However, signal integrity can be compromised due to the complex cyclic staining processes inherent to MxIF. Hematoxylin and Eosin (H&E) staining, on the other hand, offers complementary information through its dep...

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Literature Corpus work
f8c4e8be-6ca3-50c3-91db-0f7bb4409367
DOI
10.21203/rs.3.rs-5619126/v1
Open publication

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