Article
Mepolizumab induced changes in nasal methylome and transcriptome to predict response in asthma
2023-05-19
Abstract excerpt
<h4>Rationale</h4> Mepolizumab is effective for a subset of severe asthma patients in reducing exacerbation frequency. Discovery of a predictive/early marker accurately identifying patients that will have a long-term beneficial clinical response would enable targeting of treatment. <h4>Objectives</h4> We aimed to characterise the nasal methylome and transcriptome post Mepolizumab and identify signatures related to...
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Identifiers and source
- Literature Corpus work
- f8b77644-4363-5ed9-a387-deba9a01b0f6
- DOI
- 10.1101/2023.05.18.23290155