Article

Immuno-epigenetic signature derived in saliva associates with the encephalopathy of prematurity and perinatal inflammatory disorders

2022-10-20

Abstract excerpt

<h4>Background</h4> Preterm birth is closely associated with a phenotype that includes brain dysmaturation and neurocognitive impairment, commonly termed Encephalopathy of Prematurity (EoP), of which systemic inflammation is considered a key driver. DNA methylation (DNAm) signatures of inflammation from peripheral blood associate with poor brain imaging outcomes in adult cohorts. However, the robustness of DNAm in...

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Literature Corpus work: f8635ca5-7b1e-500c-a9cd-4b9afbd41422
DOI: 10.1101/2022.10.18.22281194

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