Article

<i>In situ</i> activation and heterologous production of a cryptic lantibiotic from a plant-ant derived <i>Saccharopolyspora</i> species

2019-08-13

Abstract excerpt

Most clinical antibiotics are derived from actinomycete natural products (NPs) discovered at least 60 years ago. Repeated rediscovery of known compounds led the pharmaceutical industry to largely discard microbial NPs as a source of new chemical diversity but advances in genome sequencing revealed that these organisms have the potential to make many more NPs than previously thought. Approaches to unlock NP biosynt...

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Literature Corpus work: f817442e-9078-5bfe-801e-3091d6c445e0
DOI: 10.1101/733808

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