Article

Prediction of future brain disorder risk using imaging data in 46,090 adults

2025-09-02

Abstract excerpt

<title>Abstract</title> <p>The advent of biobank level datasets offers unprecedented opportunities to discover novel imaging markers and develop prediction models for brain diseases. In this study, we first performed a prospective cohort study and derived a comprehensive atlas of 692 brain image-derived phenotypes (IDPs) associated with 22 brain diseases in 46,090 individuals from the UK Biobank, with 2,494 cases...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f8037eee-e078-549e-9c6e-3155a844286d
DOI: 10.21203/rs.3.rs-7238162/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Prediction of future brain disorder risk using imaging data in 46,090 adultsDOI 10.21203/rs.3.rs-7238162/v1Read

Prediction, prognosis and monitoring of neurodegeneration at biobank-scale via machine learning and imagingSemantic proximity Read

G2DBridge: A Multimodal Framework Linking Genetics to Disease through Imaging IntermediatesSemantic proximity Read

Atlas of the Human Brain Imaging-derived Phenotypes and Disease RiskSemantic proximity Read

Multi-organ imaging-derived polygenic indexes for brain and body healthSemantic proximity Read

Atlas of the Human Brain Imaging-derived Phenotypes and Disease RiskSemantic proximity Read

Atlas of human brain imaging-derived phenotypes and disease risk.Semantic proximity Read

Imaging-genetics-based dementia risk prediction using deep survival neural networks in the Rotterdam StudySemantic proximity Read

Causal Associations Between Imaging-derived Phenotypes and Risk of Alzheimer’s Disease and Other Neurodegenerative Disorders: A Mendelian Randomization StudySemantic proximity Read

Deep learning classification of MRI differentiates brain changes in genetic and idiopathic Parkinson’s diseaseSemantic proximity Read

Causal Associations Between Imaging-derived Phenotypes and Risk of Alzheimer’s Disease and Other Neurodegenerative Disorders: A Mendelian Randomization StudySemantic proximity Read

Imaging-genetics-based dementia risk prediction using deep survival neural networks in the Rotterdam Study.Semantic proximity Read

Interpretable MRI-Based Deep Learning for Alzheimer’s Risk and ProgressionSemantic proximity Read