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Article

Multiple particle tracking analysis in isolated nuclei reveals the mechanical phenotype of leukemia cells.

Scientific reports - 21 Apr 2020

Herráez-Aguilar Diego, Madrazo Elena, López-Menéndez Horacio, Ramírez Manuel, Monroy Francisco, Redondo-Muñoz Javier

Abstract excerpt

The nucleus is fundamentally composed by lamina and nuclear membranes that enclose the chromatin, nucleoskeletal components and suspending nucleoplasm. The functional connections of this network integrate external stimuli into cell signals, including physical forces to mechanical responses of the nucleus. Canonically, the morphological characteristics of the nucleus, as shape and size, have served for...

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Identifiers

PMID: 32317728
DOI: 10.1038/s41598-020-63682-5
PMCID: PMC7174401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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