Article

Engineering genetically-encoded synthetic biomarkers for breath-based cancer detection

2021-09-01

Abstract excerpt

Breath analysis holds great promise for rapid, noninvasive early cancer detection; however, clinical implementation is impeded by limited signal from nascent tumors and high background expression by non-malignant tissues. To address this issue, we developed a novel breath-based reporter system for early cancer detection using D-limonene, a volatile organic compound (VOC) from citrus fruit that is not produced in h...

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Literature Corpus work: f784f528-58af-5e5e-b676-f9801a5006d0
DOI: 10.1101/2021.09.01.456741

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