Article
Volatile fingerprints of cancer specific genetic mutations.
Nanomedicine : nanotechnology, biology, and medicine - 1 Aug 2013
Peled Nir, Barash Orna, Tisch Ulrike, Ionescu Radu, Broza Yoav Y, Ilouze Maya, Mattei Jane, Bunn Paul A, Hirsch Fred R, Haick Hossam
Abstract excerpt
We report on a new concept for profiling genetic mutations of (lung) cancer cells, based on the detection of patterns of volatile organic compounds (VOCs) emitted from cell membranes, using an array of nanomaterial-based sensors. In this in-vitro pilot study we have derived a volatile fingerprint assay for representative genetic mutations in cancer cells that are known to be associated with targeted cancer...
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