Article

Nucleoprotein reassortment enhanced transmissibility of H3 1990.4.a clade influenza A virus in swine

2023-10-30

Abstract excerpt

The increased detection of H3 C-IVA (1990.4.a) clade influenza A viruses (IAV) in U.S. swine in 2019 was associated with a reassortment event to acquire an H1N1pdm09 lineage nucleoprotein (pdmNP) gene, replacing a TRIG lineage NP (trigNP). We hypothesized that acquiring the pdmNP conferred a selective advantage over prior circulating H3 viruses with a trigNP. To investigate the role of the NP reassortment in trans...

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Literature Corpus work: f775c639-b5da-54dc-aa8a-723f259a3fc4
DOI: 10.1101/2023.10.30.564250

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