Article
Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs.
Scientific reports - 2 Jun 2016
Kong Weili, Liu Qinfang, Sun Yipeng, Wang Yu, Gao Huijie, Liu Lirong, Qin Zhihua, He Qiming, Sun Honglei, Pu Juan, Wang Dayan, Guo Xin, Yang Hanchun, Chang Kin-Chow, Shu Yuelong, Liu Jinhua
Abstract excerpt
Given the present extensive co-circulation in pigs of Eurasian avian-like (EA) swine H1N1 and 2009 pandemic (pdm/09) H1N1 viruses, reassortment between them is highly plausible but largely uncharacterized. Here, experimentally co-infected pigs with a representative EA virus and a pdm/09 virus yielded 55 novel reassortant viruses that could be categorized into 17 genotypes from Gt1 to Gt17 based on segment...
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