Article

Expression-Based Inference of Human Microbiome Metabolic Flux Patterns in Health and Disease

2020-01-09

Abstract excerpt

1 Metagenomic sequencing has revealed that the composition of the gut microbiome is linked to several major metabolic diseases, including obesity, type 2 diabetes (T2D), and inflammatory bowel disease (IBD). However, the exact mechanistic link between the gut microbiome and human host phenotypes is unclear. Here we used constraint-based modeling of the gut microbiome, using a gene-expression based algorithm called...

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Literature Corpus work: f76679b3-33bb-526a-9f5c-a24ed54d7fd6
DOI: 10.1101/2020.01.09.900761

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