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Schizophrenia Phenomenology Comprises a Bifactorial General Severity and a Single-group Factor, Which Are Differently Associated with Neurotoxic Immune and Immune-regulatory Pathways

2019-08-11

Abstract excerpt

In schizophrenia, a single latent trait underlies psychosis, hostility, excitation, mannerism, negative (PHEMN) symptoms, formal thought disorders (FTD) and psychomotor retardation (PMR). Schizophrenia is accompanied by a breakdown of gut and blood-brain-barrier (BBB) pathways, increased tryptophan catabolite (TRYCAT) levels, bacterial translocation, and lowered natural IgM and paraoxonase (PON)1 activity. The aim...

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Literature Corpus work
f7326f1c-9a4b-59f8-aefb-642d70981fad
DOI
10.20944/preprints201908.0132.v1
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