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Preserved Barrier Integrity and Altered Immune Profiles in Chronic Cannabis Users: Potential Roles of Δ9-Tetrahydrocannabinol

2026-07-03

Abstract excerpt

Although cannabinoids such as delta-9-tetrahydrocannabinol (THC) are generally immunosuppressive in preclinical models, chronic cannabis use in humans is paradoxically associated with increased infection risk and systemic inflammation. In this study, we demonstrate that THC directly strengthens intestinal epithelial barrier function in vitro by increasing trans-epithelial electrical resistance in a concentration-...

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Literature Corpus work
f6a2c3eb-e3ba-5ffb-8edd-8920076aa027
DOI
10.64898/2026.07.02.736074
Open publication

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Preserved Barrier Integrity and Altered Immune Profiles in Chronic Cannabis Users: Potential Roles of Δ9-TetrahydrocannabinolDOI 10.64898/2026.07.02.736074
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