Article

Radio-sensitization of mutated KRAS G12C non-small cell lung cancer with KRAS G12C tyrosine kinase inhibitor and Carbon ions irradiation

2026-04-30

Abstract excerpt

<title>Abstract</title> Non-small cell lung cancer (NSCLC) with <italic>KRAS</italic> <italic>G12C</italic> mutation is associated with poor prognosis and resistance to standard therapies. Sotorasib, a <italic>KRAS</italic> G12C tyrosine kinase inhibitor, has shown clinical efficacy, yet its interaction with different irradiation modalities remains unclear. This study aimed to...

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Literature Corpus work: f636cb59-278f-586d-9d05-8210e41f4ad1
DOI: 10.21203/rs.3.rs-9469593/v1

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