Article

Hybrid CRSIPR/Cas Protein for One-Pot Detection of DNA and RNA

2022-06-22

Abstract excerpt

Clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostics have emerged as next-generation molecular diagnostics. In the CRISPR-based diagnostics, Cas12 and Cas13 proteins have been widely employed for the detection of DNA and RNA, respectively, due to the collateral activity. Herein, a novel hybrid Cas capable of detecting universal nucleic acids (both DNA and RNA) was developed by combi...

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Literature Corpus work: f5e085d7-676c-553b-89c5-c9b34a425c54
DOI: 10.2139/ssrn.4139900

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