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CRISPR-Cas target recognition for sensing viral and cancer biomarkers

27 Aug 2024

Abstract excerpt

Nucleic acid-based diagnostics is a promising venue for detection of pathogens causing infectious diseases and mutations related to cancer. However, this type of diagnostics still faces certain challenges, and there is a need for more robust, simple and cost-effective methods. Clustered regularly interspaced short palindromic repeats (CRISPRs), the adaptive immune systems present in the prokaryotes, has recently...

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PMID: 39189452
DOI: 10.1093/nar/gkae736

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