Article

Thrombomodulin Resistance: a Novel Prothrombotic Pathway in Covid-19

2024-08-08

Abstract excerpt

<title>Abstract</title> <p>Hypercoagulability and endothelial dysfunction are strongly involved in the worsening of the clinical condition in COVID-19 patients. In severe cases, the inflammatory process triggers the release of angiopoietin 2, which could decrease circulating thrombomodulin (TM), a major regulatory mechanism in thrombin generation. Although some studies have described an increased TM resistance, f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f5cdf732-67c3-5599-858b-90d89aadb8bf
DOI: 10.21203/rs.3.rs-4731857/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Thrombomodulin Resistance: a Novel Prothrombotic Pathway in Covid-19DOI 10.21203/rs.3.rs-4731857/v1Read

Prognostic value of thrombin generation parameters in hospitalized COVID-19 patients Semantic proximity Read

Interrelationship between COVID-19 and coagulopathy: pathophysiological and clinical evidenceSemantic proximity Read

Covid-19-associated coagulopathy (CoAC): thrombin burst and insufficient fibrinolysis leading to bad outcome.Semantic proximity Read

Systemic inflammation in COVID-19 patients may induce various types of venous and arterial thrombosis: A systematic review.Semantic proximity Read

Severity-stratified and longitudinal analysis of VWF/ADAMTS13 imbalance, altered fibrin crosslinking and inhibition of fibrinolysis as contributors to COVID-19 coagulopathySemantic proximity Read

Inflammatory response in relation to COVID-19 and other prothrombotic phenotypes.Semantic proximity Read

Effect of Hereditary Thrombophilia on the Clinical Severity of Covid-19 PneumoniaSemantic proximity Read

Plasma biomarkers associated with survival and thrombosis in hospitalized COVID-19 patientsSemantic proximity Read

Coagulation Status and Venous Thromboembolism Risk in African Americans: A Potential Risk Factor in COVID-19.Semantic proximity Read

Race-Related Differences in Thrombogenicity: An Explanation for Disparities in COVID-19 Outcomes?Semantic proximity Read

Hypocoagulable Coagulation Profile and Endogenous Heparinoids Are Associated with Invasive Ventilation and Mortality in COVID-19Semantic proximity Read

Heparin Induced Thrombocytopenia in Patients with COVID-19Semantic proximity Read