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A Grape Seed Oligomeric Procyanidin Extract Reverses Diet-Induced Obesity Through Gut Microbiota Remodeling and Restoration of GLP-1, Gut-Brain, and Gut-Liver Signaling

2026-07-31

Abstract excerpt

<h4>Background</h4> Obesity is a complex multifactorial disease associated with chronic low grade inflammation, gut microbiota dysbiosis, and impaired gut-brain communication. Oligomeric procyanidins from grape seed extracts (GSE) are promising prebiotic candidates, capable of modulating host metabolism through interactions with the gut microbiota. <h4>Methods</h4> C57Bl/6J male mice were rendered obese by feedi...

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Literature Corpus work
f548fefb-4182-538b-b0d7-71a20639916d
DOI
10.64898/2026.07.31.741918
Open publication

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A Grape Seed Oligomeric Procyanidin Extract Reverses Diet-Induced Obesity Through Gut Microbiota Remodeling and Restoration of GLP-1, Gut-Brain, and Gut-Liver SignalingDOI 10.64898/2026.07.31.741918
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