Article

Dysregulation of extracellular matrix and Lysyl Oxidase in Ehlers-Danlos Syndrome Type IV skin fibroblasts

2023-09-13

Abstract excerpt

<title>Abstract</title> <p>Background Ehlers-Danlos syndrome Type IV (aka Vascular Ehlers Danlos, or vEDS) is a dominantly inherited mutation in the Collagen 3A1 gene (COL3A1). The disease is characterized by tissue friability and age-related susceptibility to arterial aneurysm, dissection and rupture as well as uterine and bowl tares. These clinical manifestations result in major surgical intervention and decre...

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Literature Corpus work: f5470a81-40e7-50be-985d-37c8ec123c21
DOI: 10.21203/rs.3.rs-3250038/v1

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