CCR4a promotes metastasis and invasion of ovarian cancer by downregulating LRRC4 via PI3K/AKT Signaling Pathway Activation

Abstract excerpt

<title>Abstract</title> <p>Background It has been established that CCR4-NOT transcription complex subunit 6 (CCR4a) can promote the growth of some malignancies. Its role and clinical significance in ovarian cancer, however, have not been documented. This article examined the spread of cancer following CCR4a modulation. Methods Bioinformatics was used to analyze the prognosis of CCR4a using the KM plot dataset....

Topics

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• Chemokine receptors and signaling
• Cytokine Signaling Pathways and Interactions
• Immune Cell Function and Interaction
• Immune cells in cancer
• Immunotherapy and Immune Responses
• Lung Cancer Research Studies
• Lung Cancer Treatments and Mutations
• T-cell and B-cell Immunology

Identifiers and source

Literature Corpus work

f5364fe5-a16d-5166-87ec-ab97bbd1c128

DOI

10.21203/rs.3.rs-5326843/v1