Article

Stage-aware transcriptomics reveals selective haplotype persistence in short-term <i>ex vivo</i> cultured <i>Plasmodium vivax</i>

2026-05-13

Abstract excerpt

Plasmodium vivax ( Pv ) infections are developmentally asynchronous and often polyclonal, complicating interpretation of bulk parasite transcriptomes. Here, we analyzed paired in vivo and short-term ex vivo transcriptomes from Ethiopian clinical isolates using stage deconvolution and PvMSP 1 haplotyping. Ex vivo maturation modestly increased inferred schizont representation while largely preserving the propor...

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Literature Corpus work: f52f9b9b-5c46-53a3-8792-4bfd17055c92
DOI: 10.64898/2026.05.11.724466

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