Article

Increased bleeding and thrombosis in myeloproliferative neoplasms mediated through altered expression of inherited platelet disorder genes

2023-05-24

Abstract excerpt

An altered thrombo-hemorrhagic profile has long been observed in patients with myeloproliferative neoplasms (MPNs). We hypothesized that this observed clinical phenotype may result from altered expression of genes known to harbor genetic variants in bleeding, thrombotic, or platelet disorders. Here, we identify 32 genes from a clinically validated gene panel that were also significantly differentially expressed in...

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Identifiers and source

Literature Corpus work: f52cfe75-b208-5285-a13d-7bd31b3c886f
DOI: 10.1101/2023.05.23.541977

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