Article

CMTM6 drives cisplatin resistance in OSCC by regulating AKT mediated Wnt signaling

2020-03-20

Abstract excerpt

Chemoresistance is one of the important factors for treatment failure in OSCC, which can culminate in progressive tumor growth and metastatic spread. Rewiring tumor cells to undergo drug-induced apoptosis is a promising way to overcome chemoresistance, which can be achieved by identifying the causative factors for acquired chemoresistance. In this study, to explore the key cisplatin resistance triggering factors,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f503d2bb-108c-570c-be09-e5a9091fb641
DOI: 10.1101/2020.03.18.993774

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CMTM6 drives cisplatin resistance in OSCC by regulating AKT mediated Wnt signalingDOI 10.1101/2020.03.18.993774Read

CMTM6 mediates cisplatin resistance in OSCC by regulating AKT/c-MYC driven ribosome biogenesisSemantic proximity Read

Prognostic Implications of Pan-cancer CMTM6 Expression and Its Relationship With the Immune MicroenvironmentSemantic proximity Read

Inhibition of miR-1307 Reverses Resistance to Cisplatin in Drug-Resistant Oral Squamous Cell CarcinomaSemantic proximity Read

Elevated H3K27me3 levels sensitize osteosarcoma to cisplatinSemantic proximity Read

The involvement of MCTP1 in the drug-resistance of esophageal cancer cellsSemantic proximity Read

ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4+ macrophage infiltrationSemantic proximity Read

Inhibition of PTK6 Hinders the Growth and Migration of Ovarian Cancer and Its Potential Clinical SignificanceSemantic proximity Read

KDM6A Loss Confers an Invasive Phenotype in Osteosarcoma by Activating Cytoplasmic YAP-Dependent β-catenin StabilisationSemantic proximity Read

Transcriptional signature of early cisplatin drug-tolerant persister cells in lung adenocarcinomaSemantic proximity Read

CD44 exerts a functional role during EMT induction in cisplatin-resistant head and neck cancer cellsSemantic proximity Read

GSDME Is Related to Prognosis and Response to Chemotherapy in Oral CancerSemantic proximity Read

Association of the Epithelial–Mesenchymal Transition (EMT) with Cisplatin ResistanceSemantic proximity Read