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GSDME Is Related to Prognosis and Response to Chemotherapy in Oral Cancer

11 Feb 2022

Abstract excerpt

Gasdermin E (GSDME), as the major executive protein of pyroptosis, has been considered to be linked to antitumor immunity in recent years. However, the role of GSDME in oral squamous cell carcinoma (OSCC) remains to be elucidated. Here, by using a human OSCC tissue microarray, human OSCC tissue, and Tgfbr1/ Pten conditional knockout mice, we found that GSDME was strongly expressed in OSCC and that GSDME...

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PMID: 35148659
DOI: 10.1177/00220345211073072

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