Article

Prediction of binding of FDA approved drug Ledipasvir to SARS-CoV2 mutants: an in silico study

2021-09-07

Abstract excerpt

The surge of variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is a global concern to public health as the mutations in the genome may alter the virulence of the virus, which poses a challenge to manage the disease. The virus depends on RNA dependent RNA polymerases [RdRp(s)] and its associated non-structural proteins for replication. Therefore, RdRp is a target of antiviral drugs. Several mu...

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Literature Corpus work: f4d6a945-8f5e-5c02-a8e3-1ac9c746b3e2
DOI: 10.21203/rs.3.rs-882289/v1

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