Article

Evolutionary analysis of the mTOR pathway provide insights into lifespan extension across mammals

2023-03-01

Abstract excerpt

<h4>Background: </h4> Lifespan extension has independently evolved several times during mammalian evolution, leading to the emergence of a group of long-lived animals. Though mammalian/mechanistic target of rapamycin (mTOR) signaling pathway is shown as a central regulator of lifespan and aging, the underlying influence of mTOR pathway on the evolution of lifespan in mammals is not well understood. <h4>Results: <...

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Literature Corpus work: f4c204fd-5c5d-52b7-b61e-a9780a76a95d
DOI: 10.21203/rs.3.rs-2384409/v1

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