Article

Antiandrogen Flutamide-Induced Restoration of miR-449 Expression Mitigates Functional Biomarkers Associated with Ovarian Cancer Risk

2024-02-28

Abstract excerpt

<h4>Background</h4> The involvement of the androgen and androgen receptor (AR) pathway in the development of epithelial ovarian cancer is increasingly recognized. However, the specific mechanisms by which anti-androgen agents, such as flutamide, may prevent ovarian cancer and their efficacy remain unknown. We examined the effects of flutamide on the miRNA expression profile found in women at high risk (HR) for ova...

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Literature Corpus work: f3c9e1cc-b0eb-5c41-b3c5-8d410f445248
DOI: 10.1101/2024.02.26.24303311

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