Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype.

International journal of molecular sciences - 23 Dec 2020

Cheung Janelle, Lokman Noor A, Abraham Riya D, Macpherson Anne M, Lee Eunice, Grutzner Frank, Ghinea Nicolae, Oehler Martin K, Ricciardelli Carmela

Abstract excerpt

Follicle-stimulating hormone (FSH) and luteinising hormone (LH) play important roles in regulating cell growth and proliferation in the ovary. However, few studies have explored the expression of FSH and LH receptors (FSHR and LHCGR) in ovarian cancer, and their functional roles in cancer progression remain inconclusive. This study investigated the potential impact of both mRNA (FSHR, LHCGR) and protein (FSHR,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms, Cystic, Mucinous, and Serous

Share to Ovarian Neoplasms

Share to Phenotype

Share to Receptors, FSH

Share to Receptors, LH

Source

Open in PubMed Open full text

Identifiers

PMID: 33374698
DOI: 10.3390/ijms22010071
PMCID: PMC7793521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reduced Gonadotrophin Receptor Expression Is Associated with a More Aggressive Ovarian Cancer Phenotype.PMID 33374698Read ↗

Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosisSemantic proximity Read ↗

Follicle-Stimulating Hormone Receptor (FSHR): A Promising Tool in Oncology?Semantic proximity Read ↗

miR-6850 Drives Phenotypic Changes and Signaling in High Grade Serous Ovarian CancerSemantic proximity Read ↗

Follicle stimulating hormone is an autocrine regulator of the ovarian cancer metastatic niche through Notch signalingSemantic proximity Read ↗

From fallopian tube epithelium to high-grade serous ovarian cancer: A single-cell resolution review of sex steroid hormone signalingSemantic proximity Read ↗

LGR4 Maintains HGSOC Cell Epithelial Phenotype and Stem-Like TraitsSemantic proximity Read ↗

MicroRNA Expression and Regulation in Human Ovarian Carcinoma Cells by Luteinizing HormoneSemantic proximity Read ↗

Progesterone limits the tumor-promoting effects of the beta-subunit of human chorionic gonadotropin via non-nuclear receptorsSemantic proximity Read ↗

Prolactin signaling drives tumorigenesis in human high grade serous ovarian cancer cells and in a spontaneous fallopian tube derived modelSemantic proximity Read ↗

Clinical Significance of Organic Anion Transporting Polypeptide Gene Expression in High-Grade Serous Ovarian CancerSemantic proximity Read ↗

Human gonadotropin-releasing hormone receptor-activated cellular functions and signaling pathways in extra-pituitary tissues and cancer cells (Review)Semantic proximity Read ↗

Hormone Receptor Expression and Disease Prognosis in High-Grade Serous Ovarian CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.