Article
CSF3-Receptor Downregulation in Bone Marrow contributes to Ineffectiveness of GCSF in Advanced Liver Cirrhosis
2021-03-30
Abstract excerpt
<title>Abstract</title> <p>Introduction: Cirrhosis patients exhibit cytopenia and variable response to GCSF, with benefits in early cirrhosis. GCSF acts through the CSF3-receptor (CSF3R), and changes in CSF3R can affect the response. We investigated the possible mechanism for the lack of efficacy of GCSF in advanced cirrhosisMethodsCirrhotic patients (n = 127) and controls (n = 26) who underwent clinically indica...
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Identifiers and source
- Literature Corpus work
- f3c589f9-9c0a-5fcd-96c0-58d4e2110824
- DOI
- 10.21203/rs.3.rs-347823/v1
