Article

scTREND: An annotation-free single-cell time-resolved and condition-dependent hazard model

2026-01-29

Abstract excerpt

Prognosis in cancer and other complex diseases is shaped by heterogeneous cell states and clinical or genetic contexts whose effects change over time. Yet most survival analyses assume predefined cell types and time-invariant covariates, and cohorts pairing single-cell transcriptomes with outcomes are limited, obscuring within-type heterogeneity, time-varying risk, and condition-specific effects. We developed scTR...

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Literature Corpus work: f35044fd-194e-518f-b9b2-037c5d6b85c6
DOI: 10.64898/2026.01.26.701686

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