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Disruption of C/EBPβ-Clec7a Axis Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-mediated Pyroptosis in Experimental Neuropathic Pain

2022-07-25

Abstract excerpt

<title>Abstract</title> <p>Background Growing evidence shows that C-Type Lectin Domain Containing 7A (Clec7a) may be involved into neuroinflammatory injury of various neurological diseases. However, its roles in neuropathic pain remain unclear. Methods A chronic constriction injury (CCI) rat model was established, and gene expression profilings in spinal cord tissues of CCI-insulted rats were detected by both m...

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Literature Corpus work: f31110c0-d4af-5dfc-96f4-0c57f8492461
DOI: 10.21203/rs.3.rs-1820808/v1

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