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Culture-enriched metagenomic sequencing reveals within-patient diversity and transmission of vancomycin-resistant <i>Enterococcus faecium</i>

2026-03-16

Abstract excerpt

Colonization of the gastrointestinal (GI) tract by vancomycin-resistant Enterococcus faecium (VREfm) often precedes bloodstream infection and serves as a reservoir for onward patient transmission in healthcare settings. Routine clonal isolate-based sequencing often underestimates within-patient diversity, and can miss transmission involving low-abundance and co-colonizing strains. Here we applied culture-enriched...

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Literature Corpus work
f2f1d408-1070-5cd3-80a8-616d7f763add
DOI
10.64898/2026.03.11.26348025
Open publication

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