Genomic epidemiology of Enterococcus faecium bloodstream infections during a VanB-type VRE peak reveals an oligoclonal scenario: an observational study at a German university hospital (2017-2022).

Abstract excerpt

A substantial and rapid increase, followed by a sharp decline in vanB-type vancomycin-resistant Enterococcus faecium (VRE), occurred in Germany in the late 2010s. This unusual epidemiological trend prompted detailed genomic investigations to explore the underlying dynamics at a German university hospital. We retrospectively analyzed 344 E. faecium bloodstream infection (BSI) isolates collected between 2017 and...

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• Bacteremia
• Enterococcus faecium
• Genome, Bacterial
• Germany
• Gram-Positive Bacterial Infections