Article

Rett syndrome from bench to bedside: recent advances

2018-03-26

Abstract excerpt

Rett Syndrome is a severe neurological disorder mainly due to de novo mutations in the methyl-CpG-binding protein 2 gene ( MECP2 ). Mecp2 is known to play a role in chromatin organization and transcriptional regulation. In this review, we report the latest advances on the molecular function of Mecp2 and the new animal and cellular models developed to better study Rett syndrome. Finally, we present the latest innov...

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Literature Corpus work: f2cc9976-dd3f-5a45-983b-2c4b8bd417f8
DOI: 10.12688/f1000research.14056.1

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