Article

Associations between structural brain changes and blood neurofilament light chain protein in treatment-resistant schizophrenia

2024-04-08

Abstract excerpt

<h4>Background and Hypothesis</h4> Around 30% of people with schizophrenia are refractory to antipsychotic treatment (treatment-resistant schizophrenia; TRS). While abnormal structural neuroimaging findings, in particular volume and thickness reductions, are often observed in schizophrenia, it is anticipated that biomarkers of neuronal injury like neurofilament light chain protein (NfL) can improve our understandi...

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Literature Corpus work: f2bac0dc-e207-5bfb-9a48-635ec054c263
DOI: 10.1101/2024.04.07.24305362

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