Article

Exosomes miR-184 and miR-3913-5p are involved in Osimertinib resistance in non-small cell lung cancer patients with exon 21 L858R mutation

2020-09-08

Abstract excerpt

<h4>Background: </h4> The third-generation of EGFR-TKI Osimertinib has become an important treatment option for patients with EGFR-mutant advanced NSCLC. In recent years, more and more studies have begun to pay attention to the ability of miRNAs in exosomes secreted by tumor cells to transmit resistance information. The mechanisms of exosomal miRNAs involved in Osimertinib resistance need to be studied. Methods W...

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Literature Corpus work: f1741577-db70-5ee9-a7bb-47f7a009b2b9
DOI: 10.21203/rs.3.rs-69938/v1

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